Is this image real or fake? has science gone too far?

The anus says that it knows

A queen winking. Her crown's got blue ornaments

John the mole says hi to dave the human

a disgustingly bloody flying eyeball.

guy with jewnose scratching his head

No men allowed!

two guys fighting the devil

a bomb

cancer

a man is disappointed at a restaurant because his meal is small. He asks the waiter about it.

animu girl with a huge head, showing her middle finger, and thin, wide, eyes.