There are many claimed "OTPs" of Homestuck, but there is only one One True Pairing: Skyhorse (Eridan's lusus) <3 Hussie

Dave is riding a giant fiery beast. He is so chill about it. Like a fucking ice man, he is.

Tavros must be on some pretty crazy drugs, cause his horns are melting. He is too scared, however, to do anything but cry softly for help.

The Mythbuster rejects your reality. It is unknown at this time whether he plans to substitute his own.

A character that I do not recognize. I'm sorry, fellow drawers. I have failed you. I must kill myself to preserve my family's honor.

Sometimes, when sentient life has really gotten him down, the Doctor will go to the end of the universe and watch the void for a bit.

An orb of aquatic energy expresses distress at the imminent collision of its bird-shaped hovercraft with the ground.

Quite a fine rainbow. The artist used the darker shade of green. A risky move, but it works quite well.

Let's do something REALLY challenging. Draw a balloon.

The TARDIS accidentally materializes in place of the Earth. This results in a paradox that screws up the universe something terrible.

A nuclear fallout zone centered in someone's crotch

Daniel Berkowitz in a tutu