Shitbob boiling in a pot of sponge.

This is Grim Fandango.

"Don't ever talk to me or my son ever again." the stern lady rhino says to you, as she towers over her crying/cowering rhino son.

A buff Japanese lady demon (an Oni?) is very sexy and very sweaty (steaming, even) and she is boxing.

I want you to draw a "Curmudgeonly Penguin." Please, I beg you, look up the word "Curmudgeonly," and you know what a penguin is. Draw that.

A young woman, on her knees, weeping openly over her dropped ice cream cone. Fred Jones is eager to make her feel better.

10k! the happy man celebrates /something/ in a flowery field.

Some kind of furry worm with huge friendly eyes is crawling towards you in a dark spooky otherworldly forest.

Launchpad McQuack, presented as a burned-out stoner who has completely fried himself, staying up all night doodling on a nice drawing tablet

A Cactus Pokemon... Cat thing.

Underaged anime girls (cast of Azumanga Daioh, I think) are disgusted by Gaston, the Disney Prince, as he flexes, trying to entice them.

Tom and Jerry, reimagined as stoner cartoon 20-something young men.